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. 2019 Apr 3;9:14. doi: 10.1038/s41387-019-0080-2

Table 2.

Proportion of medications containing phosphate as an excipient

Medications by category Number of formulations reviewed Number of formulations containing hosphorus Phosphorus-containing medications (%)
Calcium channel blockers 39 20 51
ACE inhibitors and angiotensin-receptor blockers 89 9 10
Beta blockers 39 9 23
Cholesterol-lowering therapy 38 8 21
Pain medicines 107 48 44.8
Anxiolytic agents 42 0 0
Antidepressants 173 10 5.7
Antipsychotics 54 19 35.1
Drugs used in diabetes 239 57 23.8
Psycho-analeptics 738 142 19.2
Antihypertensives 927 162 17.5
Drugs for acid-related disorders 274 45 16.4
Thyroid therapy 50 4 8
Lipid-modifying agents 354 28 7.9
Analgesics 163 11 6.7
Immunosuppressants 67 4 6
Antihistamines for systemic use 105 3 2.9
Drugs for chronic obstructive airway diseases 394 9 2.3
Antithrombotic agents 92 2 2.2
Cardiac therapy 238 5 2.1
Anti-gout preparations 12 0 0
Hormones 69 12 17
Vitamins 7 2 29
Gastrointestinal medications 213 2 0.9
Blood coagulation andformation 26 0 0

Source: bibliographic references35,36