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. 2019 Mar 28;7:62. doi: 10.3389/fbioe.2019.00062

Table 1.

A short list of topical antimicrobial agents used for burn therapy.

Agent class Specific agent/Product Application References
Topical antibiotics Mafenide acetate Clinical 2nd/3rd-degree burns Haynes, 1971
Bacitracin Clinical 2nd/3rd-degree burns Johnson et al., 1945
Mupirocin Clinical 2nd/3rd-degree burns Palmieri and Greenhalgh, 2002
Neosporin Clinical 2nd/3rd-degree burns Sinha et al., 1997
Polymyxin B Clinical 2nd/3rd-degree burns Brown and Wood, 1972
Nitrofurazone Clinical 2nd/3 rd degree burns Munster, 1984
Nystatin Clinical 2nd/3rd degree burns, fungal infections Palmieri and Greenhalgh, 2002
Silver Silver nitrate Clinical 2nd/3rd-degree burns Moyer et al., 1965
Silver sulfadiazine Clinical 2nd/3 rd degree burns Fox, 1968
Silver foams (Contreet, Allevyn) Clinical 2nd/3 rd degree burns Jørgensen et al., 2005
Flammacerium Clinical 2nd/3rd-degree burns Monafo et al., 1976
Acticoat 7 Clinical 2nd/3 rd degree burns Fong and Wood, 2006
Aquacel-Ag Clinical 2nd/3rd degree burns Barnea et al., 2010
Silvercel Clinical 2nd/3rd-degree burns Meaume et al., 2005
Silver amniotic membrane Clinical 2nd/3 rd degree burns Sawhney, 1989
Chitosan Hydrogel Clinical 2nd-degree burns Ribeiro et al., 2009
Film 2nd degree burns in rabbits Sezer et al., 2008
Bandage Mouse burn infections (Psuedomonas, Proteus) Dai et al., 2009
Antimicrobial peptide Defensins In vitro Ganz, 2009
Demegel Pseudomonas infected rat burns Chalekson et al., 2002
Histone H1.2 Pseudomonas infected rat burns Jacobsen et al., 2005
Cecropin B Pseudomonas infected mouse wounds Ren et al., 2006
rBPI Clinical trial 2nd-degree burns Steinstraesser et al., 2008
Ceragenins In vitro Epand et al., 2008

Reproduced with some modifications from (Dai et al., 2010).