Table 1.
Agent class | Specific agent/Product | Application | References |
---|---|---|---|
Topical antibiotics | Mafenide acetate | Clinical 2nd/3rd-degree burns | Haynes, 1971 |
Bacitracin | Clinical 2nd/3rd-degree burns | Johnson et al., 1945 | |
Mupirocin | Clinical 2nd/3rd-degree burns | Palmieri and Greenhalgh, 2002 | |
Neosporin | Clinical 2nd/3rd-degree burns | Sinha et al., 1997 | |
Polymyxin B | Clinical 2nd/3rd-degree burns | Brown and Wood, 1972 | |
Nitrofurazone | Clinical 2nd/3 rd degree burns | Munster, 1984 | |
Nystatin | Clinical 2nd/3rd degree burns, fungal infections | Palmieri and Greenhalgh, 2002 | |
Silver | Silver nitrate | Clinical 2nd/3rd-degree burns | Moyer et al., 1965 |
Silver sulfadiazine | Clinical 2nd/3 rd degree burns | Fox, 1968 | |
Silver foams (Contreet, Allevyn) | Clinical 2nd/3 rd degree burns | Jørgensen et al., 2005 | |
Flammacerium | Clinical 2nd/3rd-degree burns | Monafo et al., 1976 | |
Acticoat 7 | Clinical 2nd/3 rd degree burns | Fong and Wood, 2006 | |
Aquacel-Ag | Clinical 2nd/3rd degree burns | Barnea et al., 2010 | |
Silvercel | Clinical 2nd/3rd-degree burns | Meaume et al., 2005 | |
Silver amniotic membrane | Clinical 2nd/3 rd degree burns | Sawhney, 1989 | |
Chitosan | Hydrogel | Clinical 2nd-degree burns | Ribeiro et al., 2009 |
Film | 2nd degree burns in rabbits | Sezer et al., 2008 | |
Bandage | Mouse burn infections (Psuedomonas, Proteus) | Dai et al., 2009 | |
Antimicrobial peptide | Defensins | In vitro | Ganz, 2009 |
Demegel | Pseudomonas infected rat burns | Chalekson et al., 2002 | |
Histone H1.2 | Pseudomonas infected rat burns | Jacobsen et al., 2005 | |
Cecropin B | Pseudomonas infected mouse wounds | Ren et al., 2006 | |
rBPI | Clinical trial 2nd-degree burns | Steinstraesser et al., 2008 | |
Ceragenins | In vitro | Epand et al., 2008 |
Reproduced with some modifications from (Dai et al., 2010).