Table 3.

P-values, point estimates and effect sizes of patient FA values based on Crawford's modified t-test.

Patient	Fibre tract	P-value	Effect size
VS2	Left VL-M1	0.0005558⁎⁎	−4.220
	Right VL-M1	0.0000002⁎⁎	−9.247
	Left M1-DN	0.0000751⁎⁎	−5.307
	Right M1-DN	ns	–
	Left VL-DN	ns	–
	Right VL-DN	ns	–
VS7	Fibre tract	P-value	Effect size
	Left VL-M1	0.0000000⁎⁎	−12.960
	Right VL-M1	0.0000000⁎⁎	−15.444
	Left M1-DN	0.0000424⁎⁎	−5.631
	Right M1-DN	0.0006330⁎⁎	−4.151
	Left VL-DN	ns	–
	Right VL-DN	ns	–
VS8	Fibre tract	P-value	Effect size
	Left VL-M1	NA	–
	Right VL-M1	NA	–
	Left M1-DN	NA	–
	Right M1-DN	NA	–
	Left VL-DN	ns	−1.844
	Right VL-DN	0.0012831⁎	−3.781

	Fibre tract	P-value	Effect size
MCS4	Left VL-M1	ns	–
	Right VL-M1	ns	–
	Left M1-DN	ns	–
	Right M1-DN	ns	–
	Left VL-DN	ns	–
	Right VL-DN	ns	–
MCS5	Fibre tract	P-value	Effect size
	Left VL-M1	0.0011719⁎	−3.828
	Right VL-M1	0.0000706⁎⁎	−5.341
	Left M1-DN	0.0000240⁎⁎	−5.963
	Right M1-DN	0.0055660⁎	−3.018
	Left VL-DN	ns	–
	Right VL-DN	ns	–
EMCS1	Fibre tract	P-value	Effect size
	Left VL-M1	ns	–
	Right VL-M1	0.0008911⁎⁎	−3.971
	Left M1-DN	ns
	Right M1-DN	0.0001628⁎⁎	−4.878
	Left VL-DN	ns	–
	Right VL-DN	ns	–

NA: tract not available for the analysis; ns: non-significant difference.

NB. We only analysed tracts in which the FA was reduced as compared to healthy controls.

^⁎significant at 1-tail Bonferroni corrected p < .0083.

^⁎⁎significant at p < .001.