Figure 8.
Effect of TB and SA on oxidative stress, apoptosis, AchE activity and Calnexin expression of hippocampal tissues in Aβ25-35-induced mice. Activities of (A) SOD, (B) GSH-Px and (C) MDA content. (D) Hippocampal neuron apoptosis was assessed in mice using an Annexin V-EGFP/PI double staining method. (E) AchE activity in the hippocampal tissues of mice. The expression of Calnexin in the mice determined via (F) western blotting and subsequent (G) quantification. *P<0.05 vs. the control group; #P<0.05 vs. the Aβ25-35 group. TB, torenoside B; SA, savatiside A; AchE, acetylcholinesterase; Aβ, amyloid-beta; SOD, superoxide dismutase; GSH-PX, glutathione peroxidase; MDA, maleic dialdehyde.