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Tan IIA decreases β-arrestin 2 and SIRT1, and increases p65 proteins in peripheral blood mononuclear cells of patients with rheumatoid arthritis. β-arrestin 2, SIRT1 and p65 protein expression after 48 h of treatment. *P<0.05 vs. the LPS group. Tan IIA, tanshinone II A; LPS, lipopolysaccharides; SIRT1, NAD-dependent protein deacetylase sirtuin-1; p65, transcription factor p65.
