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. 2019 Mar 4;17(5):3644–3654. doi: 10.3892/etm.2019.7339

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 7. — Bioinformatics analysis of the genetic profile of the first lumbar vertebra from the Sham and OVX groups. (A and B) Statistics of enriched pathways by (A) the upregulated and (B) the downregulated differentially expressed genes in the OVX vs. Sham group. (C and D) The most enriched GO terms (OVX vs. Sham) by (C) the upregulated and (D) the downregulated differentially expressed genes. UP, upregulated; DOWN, downregulated; GO, gene ontology; Fox, forkhead box; PI3K, phosphoinositide-3 kinase; mTOR, mammalian target of rapamycin; TNF, tumor necrosis factor; HIF, hypoxia-inducible factor; AMPK, 5′ AMP-activated protein kinase; OVX, ovariectomy.