Figure 4.

Representative microscopic findings of lungs extracted from mice treated with the vehicle control, sulfasalazine alone, cisplatin alone, and their combinations in a murine lung metastasis model. A,B, H&E staining (A) and immunostaining (B) for CD44v9 in lung tissue of mice treated with the vehicle control, sulfasalazine alone, cisplatin alone, and their combinations. Scale bar = 100 μm. C, Density of CD44v9 in lung tumor nodules of the 4 treatment groups. All data are shown as mean ± SE. *P < .05, **P < .01, ***P < .001