Figure 5.

Nuclear PTMA expression predicts a favorable outcome in human bladder cancer that is associated with higher PTEN mRNA expression. A‐D, Immunohistochemical staining for PTMA expression, normal adjacent mucosa (A), negative PTMA expression (B), nuclear PTMA expression (C) and cytoplasmic PTMA expression (D) (scale bar = 50 μm, ×320). E, The association of PTMA expression pattern with tumor stage or grade. F, Kaplan‐Meier curve for disease‐free survival according to the PTMA expression pattern. G, PTEN qRT‐PCR assay using human bladder tumor specimen. N denotes nuclear; C, cytoplasmic; (−), negative PTMA expression. PTEN, phosphatase and tensin homolog; PTMA, prothymosin‐α; qRT‐PCR, quantitative reverse transcription polymerase chain reaction