miR-552-5p is overexpressed in osteosarcoma tissues and cell lines. (A) Reverse transcription-quantitative polymerase chain reaction was used to determine the expression of miR-552-5p in osteosarcoma tissues (n=51) and adjacent normal tissues (n=19). (B) Expression of miR-552-5p was assessed in metastatic and non-metastatic osteosarcoma tissues. (C) Expression of miR-552-5p was assessed in osteosarcoma cell lines, including SAOS2, MG63 and U2OS cells, and normal osteoblast hFOB1.19 cells. *P<0.05, **P<0.01 and ***P<0.001. miR, microRNA.