Table 6.

Effect of silk fibroin on cytochrome c release fibroblast and Huvec cells. The mitochondrial on fibroblast and Huvec cells (1 × 106 cells) were incubated for 12 h with various concentrations of silk fibroin. The cytochrome c release was measured using Cytochrome c ELISA kit as described in Materials

Groups		cytochrome c release
		12 h
Fibroblast	control	11.81 ± 0.002
	0.5 mg/mL	12.6 ± 0.003ns
	1 mg/mL	13.4 ± 0.002ns
	2 mg/mL	45.6 ± 0.002**
Huvec	control	13.13 ± 0.0005
	0.5 mg/mL	17.08 ± 0.004ns
	1 mg/mL	26.15 ± 0.002*
	2 mg/mL	47.70 ± 0.0125**

Values represented as mean ± SD (n = 3).

^* P < 0.05 and

^** P < 0.01 compared with control mitochondria.