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(A) Normal ovarian morphology in the sham, metformin and metformin + PDE4i groups; magnification, ×100). (B) Numerous cystic follicles were identified in the PCOS control group (haematoxylin-eosin staining; magnification, ×100). PCOS, polycystic ovary syndrome; PDE4i, phosphodiesterase 4 inhibitor.
