Table II.
Results of the 35 hub genes using the Gene Expression Profiling Interactive Analysis software.
| Hub gene | Overall survival associated | Recurrence-free survival associated | Clear cell renal cell carcinoma versus normal kidney tissue |
|---|---|---|---|
| KIF23 | √a | ||
| CDKN3 | √ | √ | Upregulated |
| TPX2 | √ | √ | Upregulated |
| BUB1B | √ | √ | Upregulated |
| CDCA8 | √ | √ | Upregulated |
| UBE2C | √ | √ | Upregulated |
| NDC80 | √ | √ | Upregulated |
| KIF15 | |||
| PBK | Upregulated | ||
| MELK | √ | Upregulated | |
| RRM2 | √ | √ | Upregulated |
| DLGAP5 | Upregulated | ||
| NCAPG | √ | √ | Upregulated |
| EXO1 | |||
| NUF2 | √ | Upregulated | |
| NCAPH | √ | √ | Upregulated |
| KIF18A | √ | ||
| PTTG1 | √ | √ | Upregulated |
| FAM64A | √ | √ | Upregulated |
| ANLN | √ | √ | Upregulated |
| SHCBP1 | |||
| CENPE | √ | ||
| MCM10 | |||
| MKI67 | Upregulated | ||
| KIF14 | √ | ||
| HMMR | √ | Upregulated | |
| KIF4A | √ | √ | Upregulated |
| CEP55 | √ | √ | Upregulated |
| CENPF | √ | √ | Upregulated |
| KIF20A | √ | √ | Upregulated |
| CDC45 | √ | Upregulated | |
| ASPM | √ | √ | Upregulated |
| NEK2 | √ | Upregulated | |
| TTK | √ | ||
| HJURP | √ | √ | Upregulated |
a
√. P<0.05; P<0.001 and |log2Fold-change|>0.585.