Figure 3.

Downregulated Krüppel‐like factor 2 (KLF2) expression promotes hepatic metastasis. A, Photograph of a liver injected with 7404/sh con cells and 7404/sh KLF2 cells. B, Hematoxylin‐eosin staining was performed on the non‐injected lobe of liver and in the lobe that was injected with 7404/sh con cells or 7404/sh KLF2 cells (scale bar: 100 μm, representative images). C, Survival time of mice injected with 7404/sh con cells or 7404/sh KLF2 cells. D,E, Terminal deoxynucleotidyl transferase dUTP nick end labeling staining was performed on the non‐injected lobe of liver injected with 7404/sh con cells or 7404/sh KLF2 cells, and a statistical analysis was performed (scale bar: 20 μm, representative images). *P < 0.05; **P < 0.01. Lentivirus was used to produce stable KLF2 transformants in 7404 cells