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. 2019 Mar 22;10:255. doi: 10.3389/fgene.2019.00255

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Copyright © 2019 Wu, Qiao, Zhao, Wu, Hu, Wu, Huang, Chen, Sun, Liu and Zhao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Elevated ECM1 expressions is significantly positively associated with increased FALEC expression in patients with GC. (A) ECM1 expression in GC tumor tissues was significantly higher than paired adjacent non-tumor samples, and a remarkable positive correlation was found between ECM1 and FALEC mRNA expression in GC by using GEPIA database (B). (C,D) shows a box plot that ECM1 expression in different histological subtypes and stages in GC patients using UALCAN database. Kaplan-Meier survival plots shown that GC patients with high ECM1 expression have reduced lower overall (E) and progression-free survival (F) rates compared with patients with low expression level of FALEC. ^∗P < 0.05, ^∗∗P < 0.01.