Figure 8.

Flu didn’t induce serious side effects in mice during the treatment. The mice in the 4T1 subcutaneous tumor model were sacrificed 17 days after the treatment. The main organs and blood of the mice were obtained for further analysis. Hematological and serum biochemistry analysis were performed after collecting eyeball blood of the mice. Heart, liver, kidney and brain of the mice were isolated and stained with H&E. (A and B) Flu treatment didn’t cause significant changes in blood hematological (A) and serum biochemistry (B) parameters. The units of the parameters are shown as follows. WBC (white blood cell) and PLT (platelet), 10⁹/L; RBC (red blood cell), 10¹²/L; ALT (alanine transarninase), AST (aspartate aminotransferase) and CK (creatinine kinase), U/L; CREA(creatinine), uM. (C) Flu didn’t cause obvious pathologic abnormalities in normal tissues of the mice. Images shown are representatives from each group. The scale bars represent 50 μm, 100 μm, 50 μm, 50 μm for heart, liver, kidney and brain, respectively.