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. 2019 Mar 1;9(3):562–573.

Figure 4.

Figure 4

Cytotoxicity of Panc02-pulsed DC-induced, unpulsed DC-induced and normal murine CD8+ T cells against Panc02 cells. After three times of IP injection, the CTL response was determined by evaluating the splenic CD8+ T-cell cytotoxicity using LDH assay. Normal murine CD8+ T cells were used as controls. IP injection of Panc02-pulsed DCs induced significantly a higher level of CTL response against Panc02 cells compared to IP injection of unpulsed DCs (E:T = 40:1, 30.80 ± 2.71% specific lysis in Panc02-pulsed DC-induced T cell/Panc02 group vs 16.74 ± 2.46% specific lysis in unpulsed DC-induced T cell/Panc02 group, or 7.28 ± 1.57% specific lysis in normal murine T cell/Panc02 group, P < 0.0001).