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HS10160 inhibits H2O2-induced PARylation in TNBC and HGSOC cell lines. Human TNBC cells (BT549 and MDA-MB-231) and HGSOC cells (DOV13 and OVCA433) were treated with indicated concentrations of PARP inhibitor HS10160 for 3 h prior to 30 min 20 mM H2O2 treatment. Cells were then subjected to Western blot analysis to determine PARylation (PAR) and PARP1 expression. Actin were used as protein quantity loading control among different samples.
