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. 2019 Mar 15;41(5):2717–2728. doi: 10.3892/or.2019.7071

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Figure 5. — Analysis of the associations between the expression of Rab1A and p-S6K1. (A) The association between Rab1A and p-S6K1 expression in 142 CRC tissues displayed as a heat map. (B) Scatter plot analysis of the relationship between Rab1A and p-S6K1 expression based on average IHC scores of five randomly selected fields-of-view and a non-parametric Spearman test was used. (C) Kaplan-Meier survival analysis of 142 CRC patients after surgery according to p-S6K1 expression. (D) Survival analysis of patients with high expression of Rab1A and p-S6K1 and low expression of either Rab1A or p-S6K1. (E) Survival analysis of patients with co-overexpression of Rab1A and p-S6K1 and patients with overexpression of Rab1A or p-S6K1 alone. CRC, colorectal carcinoma; IHC, immunohistochemical; CTL, untreated; NC, negative control shRNA; KD, shRab1A.