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. 2019 Mar 15;41(5):2717–2728. doi: 10.3892/or.2019.7071

Table IV.

Association between Rab1A/p-S6K1 positive or negative and clinicopathological factors in 142 patients with CRC.

Rab1A and p-S6K1

Factors Any-1-low Both high P-value
Sex
  Male 54 35 0.486
  Female 29 24
Age (years)
  ≤60 25 17 0.866
  >60 58 42
Size (cm)
  ≤5 52 27 0.046a
  >5 31 32
Depth of invasion
  T1-2 19 11 0.541
  T3-4 64 48
Lymph node invasion
  Negative 65 19 <0.001c
  Positive 18 40
Degree of differentiation
  Well 75 44 0.012a
  Poor   8 15
Venous invasion
  Negative 53 22 0.002b
  Positive 30 37
Neural invasion
  Negative 59 36 0.209
  Positive 24 23
TNM staging
  I–II 64 19 <0.001c
  III–IV 19 40
Tumor location
  Right 33 15 0.170
  Left 23 23
  Rectum 27 21
a

P<0.05

b

P<0.01

c

P<0.001. CRC, colorectal cancer; TNM, tumor-lymph node metastasis.