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Schema of the mechanism between PRL-3, MAPK and NF-κB. PRL-3, phosphatase of regenerating liver-3; CRC, colorectal cancer; EMT, epithelial-mesenchymal transition; CCL26, chemokine ligand 26; IL, interleukin; CCR3, C-C chemokine receptor type 3; MAPK, mitogen-activated protein kinase; TAM, tumor-associated macrophages.
