Table 4.
Disease Control and Outcomesa.
| Variable | % (n) of Patients |
|---|---|
| Local recurrence event, n = 1229 | 42.6% (523) |
| Local recurrence, time to (months), n = 275 | |
| Time to, mean | 40 ± 19 |
| Time to, range | 1-228 |
| Distant recurrence event, n = 921 | 22.4% (206) |
| Distant recurrence, time to (months), n = 75 | |
| Time to, mean | 60. ± 30. |
| Time to, range | 0-228 |
| Location of distant recurrence, nb = 127 | |
| Lung | 68.5% (87) |
| Liver | 6.3% (8) |
| Spine | 8.7% (11) |
| Elsewhere | 16.5% (21) |
| Oncologic status at end of follow-up, n = 776 | |
| Continuously disease free | 23.7% (184) |
| No evidence of disease | 29.5% (229) |
| Alive with disease | 15.6% (121) |
| Dead of disease/treatment | 26.7% (207) |
| Dead of other causes | 3.7% (29) |
| Lost to follow-up | 0.8% (6) |
Abbreviation: n, number of patients at risk (in studies reporting characteristic).
aOf 1229 patients with local control follow-up in this study, 43% experienced a local recurrence. The mean time to local recurrence was 40 ± 19 (1-228) months after surgery.
bNumber of metastases (not necessarily patients) with known location.