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. 2019 Jan 31;42(4):zsz020. doi: 10.1093/sleep/zsz020

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Figure 3. — Effects of alcohol withdrawal and subsequent suvorexant administration on REM patterns. Latency to first REM episode, total number of REM episodes, their average duration, and REM sleep fragmentation ratio (total episodes/average duration) are shown for the alcohol vapor–exposed animals and their controls. Means and standard errors shown, asterisk, * indicates significant (p < 0.05) post hoc by condition compared with baseline or vehicle condition, plus sign, + indicates significant (p < 0.05) post hoc by group treatment. FCTX = frontal cortex; PCTX = parietal cortex; BL = baseline; WD = withdrawal; VEH = Vehicle; LD = low-dose suvorexant 10 mg/kg; HD = high-dose suvorexant 30 mg/kg.