Table 3.

Association between changes in leptin levels with changes in metabolic and PA parameters: multivariable linear regression analysis in children with abdominal obesity

	% Δ leptin
	Crude regression		Adjusted regression1
	β	P	β	p
% Δ BMI-SDS	0.176	< 0.001	0.146	0.001
% Δ waist circumference	0.040	< 0.001	0.051	< 0.001
% Δ Waist-to-height ratio	0.041	< 0.001	0.050	< 0.001
% Δ glucose	0.009	0.639	0.040	0.077
% Δ insulin	0.194	0.049	0.244	0.055
% Δ HOMA-IR	0.187	0.077	0.271	0.050
% Δ Sleep time	−0.035	0.573	−0.119	0.083
% Δ Sedentary PA	0.003	0.973	0.111	0.241
% Δ LPA	0.020	0.670	0.001	0.994
% Δ MVPA	−0.088	0.888	−2.173	0.007

Abdominal obesity was defined as WC above the sex and age-specific 90th percentile. ¹ The regression model was adjusted for the corresponding variable at baseline, BMI-SDS, sex and Tanner stage

Abbreviations: BMI-SDS Standard deviation score for body mass index, LPA Light physical activity, MVPA Moderate-to-vigorous physical activity, PA Physical activity

P values below 0.05 are written in boldface