Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The acetyl-lysine (KAc) binding pockets of two human bromodomains were identified by DoGSiteScorer. (A) shows the non-druggable KAc binding site of the bromodomain from TRIM24 (PDB: 2YYN_A) (druggability score =0.49). (B) shows the druggable KAc binding site of the bromodomain from BRD1 (PDB: 3RCW_A) ( druggability score =0.68). A score greater than 0.50 is indicative of a druggable pocket [102].
