Table 2.
Potential bleeding risk factors.
| Risk factor | Tirofiban (n = 18) | Aspirin (n = 14) | p-value |
|---|---|---|---|
| Vitals and laboratory parameters | |||
| Systolic blood pressure on admission in mmHg, median (IQR) | 140 (130–160) | 161 (140–181) | 0.12 |
| Creatinine on admission (µL/mL), median (IQR) | 87 (71–94) | 79 (61–94) | 0.23 |
| Glucose level on admission, median (IQR) | 6.5 (5.6–7.2) | 6.1 (5.6–7.7) | 1 |
| Platelet count on admission (G/L), median (IQR) | 248 (207–282) | 211 (163–278) | 0.39 |
| INR on admission, median (IQR) | 1 (1–1) | 1.1 (1–1.2) | 0.033 |
| Medication | |||
| Prior antiplatelet therapy, n (%) | 2 (11%) | 3 (23%) | 0.37 |
| Peri-interventional heparin (dose in U/L), median (IQR) | 1625 (1000–3200) | 4800 (1300–5000) | 0.18 |
| Radiological parameters | |||
| ASPECT score, median (IQR) | 8 (7–9) | 9 (8–9) | 0.53 |
| Collateral score according Maas et al.,9 median (IQR) | 3 (3–4) | 3 (3–4) | 0.54 |
| ICA NASCET score, median (IQR) | 91 (86–100) | 88 (76–99) | 0.28 |
| TICI scale grade ≥ 2 b | 13 (72%) | 11 (85%) | 0.42 |
| Stroke volume (mL), median (IQR) | 43 (12.2–126.7) | 40.5 (12.6–99.2) | 0.97 |
| Temporal parameters | |||
| Time of stroke onset to intravenous thrombolysis in minutes, median (IQR) | 136 (105–150) | 115 (81–120) | 0.41 |
| Time of stroke onset to groin puncture in minutes, median (IQR) | 237 (187–285) | 243 (187–295) | 0.83 |
| Duration of endovascular intervention in minutes, median (IQR) | 129 (116–154) | 163 (92–205) | 0.29 |
ASPECT score = Alberta Stroke Programme Early CT score; ICA = internal carotid artery; IQR = interquartile range; NASCET = North American Symptomatic Carotid Endarterectomy Score; TICI Scale grade = Thrombolysis in Cerebral Infarction Scale grade.