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. 2019 Mar 28;10:278. doi: 10.3389/fgene.2019.00278

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Copyright © 2019 Zhang, Duan, Cun and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Prognostic SFs and the splicing correlation network in BRCA. (A,B) Survival curves of prognostic SFs. (C,D) The difference of expression values of prognostic SFs between primary BRCA and paired adjacent normal tissues. (E) Construction of SF-AS regulatory network. Expression values of survival-associated SFs (blue dots) were positively (red line) or negatively (green line) correlated with PSI values of AS events included in all types of AS signatures. The protective AS events are indicated by green dots while risky AS events are indicated by red dots.