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. 2019 Apr 4;2019(4):CD010880. doi: 10.1002/14651858.CD010880.pub2

Druss 2010.

Methods Allocation: randomised
Blindness: single blinded
Study duration: 6 months
Location: single centre
Design: parallel
Setting: outpatients
Country: USA
Consent: written
Participants Diagnosis: schizophrenia (28.8%), bipolar disorder (32.5%), major depression (26.3%), PTSD (11.3%)
N = 80
History: not stated
Sex: men 24, women 56
Age: mean 47.8, SD 10.1 years
Exclusion criteria: not stated
Interventions Group 1: peer‐support + standard care (n = 41).
Content: 6 group sessions led by peer specialists, discussed the following topics: overview of self‐management; exercise and physical activity; pain and fatigue management; healthy eating on a limited budget; medication management; finding and working with a regular doctor.
Delivered by: trained peer specialists.
Frequency: peer support specialists.
Treatment duration: 6 months.
Group 2: standard care (n = 39).
Content: receiving all medical, mental health and peer‐based services that they were otherwise receiving prior to entry into the study.
Treatment duration: 6 months.
Outcomes Service use: clinically important engagement
Behaviour: patient activation
Leaving the study early
Peer outcomes: quality of life for participant and peer supporter
Unable to use
Global state: compliance with medication (see What's new)
Notes Funding source: NIMH R34MH078583.
We contacted the author to clarify whether peer support group received standard care; however, we received no reply. Usually outpatients in the usual care setting normally receive usual psychiatric care and thus are not deprived of any standard care or service in the community.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Quote: "Using a computerized algorithm, patients were randomised to the intervention or standard care group by the project manager."
Comment: adequate sequence generation.
Allocation concealment (selection bias) Unclear risk Comment: author did not describe allocation concealment. Insufficient information to permit judgement of low risk or high risk.
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Quote: "The interviewers were blinded to subjects' randomisation status."
Comment: blinding of personnel ensured. No blinding information for participants.
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk Quote: "The interviewers were blinded to subjects' randomisation status."
Comment: blinding of assessors ensured
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Comment: 4 participants lost from intervention group and 11 participants lost from standard care group (data from Figure 1 of the publication), with reasons such as unable to locate, deceased and withdrawn. Analysis was included for attrition.
Selective reporting (reporting bias) Unclear risk Comment: study protocol not available. Insufficient information to make judgement.
Other bias Low risk None noted.