Table 2.

Comparison of experimental and predicted values under optimal conditions for final formulation

Measured responses	Predicted	Experimental	Bias (%)
Particle size (nm)	140.2	146.7	−4.64
% Entrapment efficiency	76.90	74.22	3.49
% Drug loading	4.76	4.89	−2.73

Note: Bias was calculated as (predicted value − experimental value)/predicted value × 100%.