Table 1.
Amino acid sequences, net charge at 7.0, and GRAVY score of peptide hits found by phage display screening against CF mucus. Net charge was calculated by Protein Calculator v3.4 (The Scripps Research Institute, La Jolla, CA. Available at http://protcalc.sourceforge.net/), and GRAVY score was calculated according to the literature (Kyte and Doolittle, 1982).
Phage clone | Sequence | Net charge at pH 7.0 | GRAVY score |
---|---|---|---|
SSQ | SSQLSRPGGGS | 0.9 | −0.927 |
ISL | ISLPSPTGGGS | −0.1 | 0.073 |
YNS | YNSPTHHGGGS | 0.4 | −1.482 |