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. Author manuscript; available in PMC: 2019 Dec 20.
Published in final edited form as: Int J Pharm. 2018 Sep 27;553(1-2):57–64. doi: 10.1016/j.ijpharm.2018.09.055

Table 2.

Diffusion coefficients of phage clones in PBS and CF mucus (CM), and ratios of the average apparent diffusion coefficients in PBS (DPBS) compared to CF mucus (DCM). DH, apparent hydrodynamic diameter, D, apparent diffusion coefficient, PBS, phosphate buffered saline, CM, CF mucus.

Phage clone DH, nma D, 10−9 cm2 s−1 DPBS/DCMc
PBSb CM
M13KE 95.09 ± 4.72 51.9 ± 2.6 0.18 ± 0.03 288
SSQ 98.20 ± 2.87 50.2 ± 1.5 0.20 ± 0.11 251
ISL 90.26 ± 2.38 54.6 ± 1.4 0.47 ± 0.16 116
YNS 112.03 ± 1.02 43.9 ± 0.4 0.17 ± 0.04 258
a

Determined by dynamic light scattering.

b

DPBS is calculated from the Stokes-Einstein equation.

c

The DPBS/DCM ratio indicates by what multiple the average diffusion coefficient in CF mucus is slower than in saline.