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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Nov 22;1864(2):158–167. doi: 10.1016/j.bbalip.2018.11.002

Fig. 1. GLTP overexpression inhibits growth in human colon carcinoma cell lines but spares normal colon cells.

Fig. 1

(A) HT-29 and (B) CCD-18Co cells analyzed for cell growth following 24, 48 and 72 h post transfection with FLAG-tagged empty vector (Control Vector), GLTP overexpression vector (FLAG-GLTP), W96A-GLTP mutant with an ablated glycolipid binding site vector (FLAG-W96AGLTP), GLTP depletion vector (siGLTP) and non-targeting siRNA control vector (siCtrl). Total cells were collected and counted by hemocytometry. Experiments were done in triplicate and values represent means ± sem. *P<0.05, **P<0.01, **P<0.001 Student t-test. (see Supplemental Fig. S2 for HCT-116 cell data)