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. 2013 Apr 24;2(2):64–67. doi: 10.1002/cld.172

Table 1.

Histological Findings in ALD

Steatosis Alcoholic (Steato‐) Hepatitis Steatofibrosis Miscellaneous
Classic findings Small‐ and large‐droplet fat Beginning and/or most prominent in perivenular regions (acinus zone 3) and extending with increasing severity toward portal tracts Hepatocyte ballooning with and without Mallory‐Denk bodies and/or neutrophil‐rich parenchymal inflammation Perivenular and pericellular fibrosis (chicken‐wire fence pattern) Central‐central and/or central‐portal fibrous septa Micronodular (Laennec's cirrhosis) Megamitochondria
Other possible findings Diffuse microvesicular steatosis indicative of alcoholic foamy degeneration Mixed inflammatory infiltrates Features of fibrotic regression after sustained abstinence Hepatocellular iron (whether it is related to alcohol use or concomitant hereditary hemochromatosis requires a clinical assessment)