Table 2.

Current Indications of Antibiotic Prophylaxis in Cirrhosis

Indication	Antibiotic Regimen	Duration
Gastrointestinal bleeding	Norfloxacin 400 mg/12 hours by mouth	Seven days
	Intravenous ceftriaxone 1 g/day in patients with advanced cirrhosis (at least two of the following: ascites, jaundice, hepatic encephalopathy, malnutrition)
Low protein ascites (<15 g/L) and advanced cirrhosis	Norfloxacin 400 mg/day PO in patients with renal dysfunction (serum creatinine ≥1.2 mg/dL, blood urea nitrogen ≥25 mg/dL, or serum sodium ≤130 mEq/L) and/or poor liver function (Child‐Pugh score ≥9 with serum bilirubin ≥3 mg/dL)	Until liver transplantation, disappearance of ascites, or death
Secondary prophylaxis for SBP	Norfloxacin 400 mg/day by mouth	Until liver transplantation or death