Patients with CKD stage I to III (creatine clearance > 30 ml/min)
First‐line treatment	Pegylated IFN, renally dosed ribavirin, and sofosbuvir
Alternate treatment	Pegylated IFN, renally dosed ribavirin, and simeprevir (for genotype 1b; and for 1a if no Q80K mutation)
Patients with CKD IV or V
First‐line treatment	Pegylated IFN and ribavirin 200 mg daily