Table 1. known factors involved in mitochondrial fission in yeast, humans and plants and their conservation in T. gondii genome.
| Protein name | Function | Toxoplasma gondii homolog |
|---|---|---|
| Drp1 (human)/Dnm1(yeast)/Drp3A-B(plants) | Dynamin related protein | TgDrpA (TGME49_267800), TgDrpB (TGME49_321620), TgDrpC (TGME49_270690) |
| Fis1 (human, yeast, plants) | Mitochondrial outer membrane adaptor | TgFis1 (TGME49_263323) |
| Mdv1/Caf4/Num1/Mdm36 (yeast) | Mitochondrial receptor for Dnm1 | - |
| Mff (Human) | Recruitment of Drp1 to the mitochondrial membrane | - |
| MiD49/50 (Human) | Drp1 receptor | - |
| ELM1 (plants) | Recruitment of Drp3 to the mitochondrial membrane | - |