Table 2. Performances comparison between S4TE 1.0 and S4TE 2.0 algorithms with or without the homology search module.

Software	S4TE 1.0		S4TE 2.0
Homology	With	Without	With	Without
Sensitivity	0.86	0.16	1	0.41
Specificity	0.97	0.97	0.93	0.93
Positive Predictive Value	0.74	0.44	0.60	0.43
Negative Predictive Value	0.98	0.91	1	0.94