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. 2019 Apr 4;14(4):e0214795. doi: 10.1371/journal.pone.0214795

Table 2. Adverse events reported among chronic hepatitis C patients treated at a single centre in Germany.

Adverse events, n (%) SOF/VEL
overall (n = 115)
LDV/SOF overall
(n = 249)
Patients with any AEs (Grades 3 & 4) 1 (0.9) 13 (5.2)
AEs 'probably' or 'possibly' related to treatment 2/2 (100) 10/13 (76.9)
AEs 'possibly' or 'possibly' related to SOF-treatment 2/2 (100) 3/13 (23.1)
AEs leading to discontinuation 2/2 (100) 0/13 (0.0)
AEs leading to hospitalization 0/2 (0.0) 0/13 (0.0)
Death 0/2 (0.0) 0/13 (0.0)

AEs: adverse events; LDV: ledipasvir; SOF: sofosbuvir; VEL: velpatasvir