Fig 6. High-density growth and wound fitness correlate.
(A and B) Relationship between the competitive index of mutants in colonies (A) or stationary phase cultures (B) and in wound infections. Spearman correlation and significance values were calculated using mean competitive index of each mutant. C. The wound competitive index of the 100 mutants exhibiting the lowest and highest stationary phase culture fitness (as measured by Tn-seq). Box plots indicate median, and 25th and 75th percentiles; error bars show the range of wound competitive index. Significance determined by Mann-Whitney analysis.