Table 5.

 Correlations between DNA methylation (β values) of five replicated CpGs with type 2 diabetes risk factors in healthy individuals in Lifelines sample (n = 98)

	ABCG1		LOXL2		TXNIP		SLC1A5		SREBF1
	r	p value	r	p value	r	p value	r	p value	r	p value
Age	0.31	1.7 × 10−3	−0.17	8 × 10−2	−0.11	3.4 × 10−2	−0.27	6.6 × 10−3	0.45	4.4 × 10−6
Fasting glucose	0.31	1.9 × 10−3	−0.09	0.33	−0.15	0.14	−0.01	0.86	0.21	3.5 × 10−2
Triacylglycerol	0.25	1.3 × 10−2	−0.11	0.26	−0.17	9 × 10−2	−0.13	0.18	0.23	2.2 × 10−2
Total cholesterol	0.15	0.14	−0.10	0.32	−0.11	0.24	0.03	0.75	0.44	6.7 × 10−6
LDL-cholesterol	0.15	0.13	0.11	0.25	−0.14	0.16	−0.03	0.71	0.41	2.8 × 10−5
HDL-cholesterol	−0.07	0.46	0.04	0.65	0.09	0.37	0.27	6.4 × 10−3	0.07	0.44
BMI	0.19	0.065	−0.1	0.35	−0.12	0.26	−0.16	0.1	0.15	0.12

r = Pearson’s correlation coefficient

Significant p values < 0.05