Table 4.
Baseline biochemistry by study area (ITT population)
| All | Scotland | Tyneside | p value | |
|---|---|---|---|---|
| n (missing) | 291 (7) | 196 (1) | 95 (6) | |
| Total cholesterol (mmol/l) | 4.32 (1.19) | 4.38 (1.21) | 4.19 (1.13) | 0.239 |
| HDL-cholesterol (mmol/l) | 1.12 (0.28) | 1.14 (0.28) | 1.08 (0.29) | 0.043 |
| Triacylglycerol (mmol/l) | 2.00 (1.17) | 2.10 (1.27) | 1.80 (0.89) | 0.034 |
| ALT (U/l) | 34.1 (19.4) | 34.8 (20.1) | 32.7 (17.8) | 0.450 |
| AST (U/l) | 24.2 (12.8) | 24.8 (13.1) | 22.8 (12.2) | 0.136 |
| GGT (U/l) | 52.4 (56.8) | 54.5 (62.8) | 48.0 (41.7) | 0.567 |
| Creatinine (μmol/l) | 68.3 (15.1) | 70.7 (15.1) | 63.3 (13.9) | <0.001 |
| eGFR (ml min−1 1.73 m−2) | 98.6 (24.7) | 94.3 (22.0) | 107.5 (27.4) | <0.001 |
| n (missing) | 292 (6) | 196 (1) | 96 (5) | |
| Glucose (mmol/l) | 9.01 (2.94) | 9.30 (2.94) | 8.43 (2.85) | 0.010 |
| Insulin (mU/ml) | 23.50 (14.35) | 25.34 (14.58) | 19.67 (13.13) | <0.001 |
| n (missing) | 292 (6) | 197 (0) | 95 (6) | |
| ACR (mg/mmol)a | 2.16 (6.89) | 1.71 (6.73) | 3.08 (7.16) | 0.414 |
| Microalbuminuria, n (%)b | 39 (13.4) | 18 (9.1) | 21 (22.1) | 0.003 |
Data are mean (SD) unless otherwise stated
aValues <0.5 imputed as 0.25
bDefined as ACR ≥3.5 (female) or ACR ≥2.5 (male)