Table 1.
Baseline descriptive statistics stratified by age groups.
| Variable | Missing data, n (%) | Overall | 18–44 years of age | 45–59 years of age | 60–74 years of age | ≥75 years of age |
|---|---|---|---|---|---|---|
| n | 100,606 | 8642 | 30,907 | 45,269 | 15,788 | |
| Follow-up time (years) | 2.8 (2.5) | 2.5 (2.5) | 2.9 (2.6) | 2.9 (2.5) | 2.7 (2.3) | |
| Sex, women | 0 (0.0) | 44,925 (44.7) | 3442 (39.8) | 11,695 (37.8) | 19,865 (43.9) | 9923 (62.9) |
| Age (years) | 0 (0.0) | 62.0 (12.3) | 38.3 (5.6) | 53.1 (4.2) | 66.2 (4.1) | 80.4 (4.4) |
| HbA1c | 8208 (8.2) | |||||
| mmol/mol | 49.2 (11.0) | 51.5 (14.6) | 50.4 (12.3) | 48.2 (9.7) | 48.5 (9.4) | |
| % | 6.7 (1.0) | 6.9 (1.3) | 6.8 (1.1) | 6.6 (0.9) | 6.6 (0.9) | |
| >53 mmol/mol | 16, 462 (17.6) | 1782 (32.4) | 6001 (28.0) | 6360 (20.0) | 2319 (20.8) | |
| BMI (kg/m2) | 25,701 (25.5) | 30.6 (5.7) | 33.4 (7.3) | 31.5 (5.8) | 30.2 (5.2) | 28.3 (4.7) |
| BMI >30 kg/m2 | 25,701 (25.5) | 36,437 (48.6) | 4131 (65.3) | 12,964 (55.7) | 15,753 (46.3) | 3589 (31.9) |
| SBP (mmHg) | 18,480 (18.4) | 137.3 (17.3) | 128.4 (15.3) | 134.9 (16.5) | 139.1 (16.9) | 141.6 (18.3) |
| Systolic hypertension (>140 mmHg) | 18,480 (18.4) | 26,766 (32.6) | 982 (14.8) | 6737 (26.9) | 13,502 (36.2) | 5545 (42.0) |
| DBP (mmHg) | 18,480 (18.4) | 79.7 (10.0) | 80.5 (10.5) | 82.0 (9.9) | 79.4 (9.6) | 75.6 (9.8) |
| Diastolic hypertension (>90 mmHg) | 18,480 (18.4) | 7918 (9.6) | 809 (12.2) | 3494 (14.0) | 3109 (8.3) | 506 (3.8) |
| Total cholesterol (mmol/l) | 33,648 (33.4) | 5.3 (1.2) | 5.3 (1.2) | 5.4 (1.2) | 5.2 (1.1) | 5.1 (1.1) |
| Hypercholesterolaemia (>6.2 mmol/l) | 33,648 (33.4) | 12,208 (18.2) | 939 (17.7) | 4401 (20.8) | 5519 (17.6) | 1349 (14.8) |
| LDL-cholesterol (mmol/l) | 42,691 (42.4) | 3.1 (1.0) | 3.2 (1.0) | 3.2 (1.0) | 3.1 (1.0) | 3.0 (1.0) |
| HDL-cholesterol (mmol/l) | 40,893 (40.6) | 1.2 (0.4) | 1.1 (0.3) | 1.2 (0.4) | 1.3 (0.4) | 1.3 (0.4) |
| Triacylglycerol (mmol/l) | 40,037 (39.8) | 2.0 (1.4) | 2.4 (1.8) | 2.2 (1.6) | 1.9 (1.2) | 1.7 (0.9) |
| Microalbuminuriaa | 51,166 (50.9) | 6110 (12.4) | 492 (11.6) | 1820 (11.6) | 2732 (12.2) | 1066 (15.1) |
| eGFR (ml/min) | 22,951 (22.8) | 84.8 (25.2) | 105.8 (26.9) | 93.5 (25.3) | 81.8 (21.1) | 67.0 (19.9) |
| Smoker | 22,205 (22.1) | 14,257 (18.2) | 1540 (24.1) | 6117 (25.2) | 5875 (16.5) | 725 (5.9) |
| Medication useb | ||||||
| Antihypertensive agents | 7845 (7.8) | 57,686 (62.2) | 1801 (23.1) | 14,499 (51.2) | 29,630 (70.5) | 11,756 (80.4) |
| Statins | 7927 (7.9) | 35,582 (38.4) | 1285 (16.3) | 9575 (33.6) | 19,029 (45.4) | 5693 (39.5) |
| No medication | 0 (0.0) | 52,491 (52.2) | 3824 (44.2) | 14,094 (45.6) | 24,533 (54.2) | 10,040 (63.6) |
| Oral glucose-lowering agents | 0 (0.0) | 38,582 (38.3) | 3973 (46.0) | 13,197 (42.7) | 16,894 (37.3) | 4518 (28.6) |
| Insulin | 0 (0.0) | 5589 (5.6) | 525 (6.1) | 2031 (6.6) | 2194 (4.8) | 839 (5.3) |
| Insulin + oral glucose-lowering agents | 0 (0.0) | 3944 (3.9) | 320 (3.7) | 1585 (5.1) | 1648 (3.6) | 391 (2.5) |
| Marital status | 448 (0.4) | |||||
| Single | 18,283 (18.3) | 4099 (47.5) | 8155 (26.5) | 5212 (11.6) | 817 (5.2) | |
| Married | 53,276 (53.2) | 3587 (41.6) | 15,933 (51.7) | 26,678 (59.2) | 7078 (45.3) | |
| Separated | 17,917 (17.9) | 910 (10.5) | 6194 (20.1) | 9042 (20.1) | 1771 (11.3) | |
| Widowed | 10,682 (10.7) | 35 (0.4) | 549 (1.8) | 4152 (9.2) | 5946 (38.1) | |
| Country of birth | 0 (0.0) | |||||
| Sweden | 81,545 (81.1) | 5839 (67.6) | 23,267 (75.3) | 38,412 (84.9) | 14,027 (88.8) | |
| Europe (excl. Sweden) | 10,612 (10.5) | 710 (8.2) | 3441 (11.1) | 5047 (11.1) | 1414 (9.0) | |
| Rest of world | 8449 (8.4) | 2093 (24.2) | 4199 (13.6) | 1810 (4.0) | 347 (2.2) | |
| Education | 1881 (1.9) | |||||
| Elementary school | 36,743 (37.2) | 1881 (22.2) | 8099 (26.5) | 17,687 (39.8) | 9076 (59.6) | |
| College level | 44,029 (44.6) | 4719 (55.8) | 15,862 (51.9) | 18,939 (42.6) | 4509 (29.6) | |
| Upper/secondary school | 17,953 (18.2) | 1858 (22.0) | 6617 (21.6) | 7827 (17.6) | 1651 (10.8) |
All data are based on the first observation after diagnosis, except for HbA1c where the first observation 1 year after diagnosis was used
All continuous variables are represented as mean (SD). Dichotomous variables are represented as number of individuals (%).
aMicroalbuminuria was defined as two positive results for three samples obtained within 1 year of each other, with an albumin/creatinine ratio of 3–30 mg/mmol or a urinary albumin clearance of 20–200 μg/min
bInitial medication data were obtained within 3 months of diagnosis