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. 2018 Jan 18;61(4):849–861. doi: 10.1007/s00125-017-4521-y

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — (a) Flowchart of participant selection from the Västerbotten Intervention Programme cohort. (b) Information on baseline and 10 year follow-up sampling among 187 type 2 diabetes cases. Group A, where the second sample was drawn before (median 2 years) type 2 diabetes diagnosis (n = 26 pairs); group B, where the second sample was drawn in the same year of type 2 diabetes diagnosis (n = 52 pairs); group C, where the second sample was drawn after (median 4 years) type 2 diabetes diagnosis (n = 109 pairs)