Fig. 3.

 Expression of FAM13A (a), POM121C (b), SNRPC (c) and UHRF1BP1 (d) was knocked down using siRNA in hMSCs in vitro at day 4 of differentiation until day 7 and 12 of differentiation, upon which the expression of target and ADIPOQ, CEBPA, SLC2A4, LIPE and PPARG was monitored. We have performed three biological experiments with 3–4 technical replicates in each experiment; n = 11 technical replicates for NegC; n = 12 technical replicates for target genes. Results were analysed using the paired t test and are presented as relative fold change±SD vs negative control (NegC) at each time point during differentiation. Black bars, day 7; white bars, day 12. *p < 0.05, **p < 0.01 and ***p < 0.001 vs NegC