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. 2018 Feb 24;61(5):1167–1179. doi: 10.1007/s00125-018-4571-9

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 5 — Suppression of IFI16 in human SGBS pre-adipocytes decreases ZNF423 expression and adipocyte differentiation. (a) IFI16 and (b) ZNF423 mRNA levels in human SGBS pre-adipocytes at the indicated time points during early differentiation (n = 6). (c) Study design of SGBS cell experiments. (d, e) Quantitative real-time PCR analysis of indicated genes on (d) day 2 and (e) day 3 after IFI16 depletion via siRNA. White bars, non-target siRNA; black bars, IFI16 siRNA (si-IFI16). Data are mean ± SEM (non-target si RNA, n = 9; si-IFI16, n = 8). *p < 0.05 and ***p < 0.001 (Student’s t test)