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. Author manuscript; available in PMC: 2019 Apr 30.
Published in final edited form as: Analyst. 2018 Apr 30;143(9):2057–2065. doi: 10.1039/c7an02024d

Scheme 1.

Scheme 1.

Schematic description of the conventional ELSIA (A), the biotin-avidin-amplified ELISA using chemical biotinylated scFv (B), and the biotin-avidin-amplified ELISA using enzymatic biotinylated scFv (C).