Table 2.
Statistical tests table
| Figure | Data structure | Type of test | Statistical data |
|---|---|---|---|
| 1I | Normal | One-way RM ANOVA | Level: F(1.65,6.60) = 1.225, p = 0.34 |
| distribution | (Geisser-Greenhouse correction) | Animal: F(4,16) = 5.038, p = 8.04e-3 | |
| Tukey’s multiple comparisons test | |||
| Level 1 vs level 2, q = 1.04, p = 0.94 | |||
| Level 1 vs level 3, q = 2.11, p = 0.62 | |||
| Level 1 vs level 4, q = 1.80, p = 0.72 | |||
| Level 1 vs level 5, q = 1.07, p = 0.93 | |||
| Level 2 vs level 3, q = 10.01, p = 9.83e-3 | |||
| Level 2 vs level 4, q = 5.23, p = 8.90e-2 | |||
| Level 2 vs level 5, q = 0.25, p = 0.99 | |||
| Level 3 vs level 4, q = 2.68, p = 0.44 | |||
| Level 3 vs level 5, q = 1.57, p = 0.80 | |||
| Level 4 vs level 5, q = 1.21, p = 0.90 | |||
| Figure | Data structure | Type of test | Statistical data |
| 2C | Normal | Paired t test | t = 11.98, df = 8, p = 2.17e-6 |
| Restored group | distribution | ||
| Figure | Data structure | Type of test | Statistical data |
| 3A | Growth curve | Two-way ANOVA | Interaction F(18,384) = 8.76, p < 1.00e-15 |
| Males | Time: F(9,384) = 244, p < 1.00e-15 | ||
| Genotype: F(2,384) = 198.2, p < 1.00e-15 | |||
| Tukey’s multiple comparisons test | |||
| Five weeks: | |||
| Control vs FNΔ2, q = 3.23, p = 5.97e-2 | |||
| Control vs restored, q = 0.80, p = 0.84 | |||
| FNΔ2 vs restored, q = 2.80, p = 0.12 | |||
| Six weeks: | |||
| Control vs FNΔ2, q = 4.34, p = 6.46e-3 | |||
| Control vs restored, q = 0.00, p > 0.99 | |||
| FNΔ2 vs restored, q = 4.66, p = 3.07e-3 | |||
| Seven weeks: | |||
| Control vs FNΔ2, q = 5.46, p = 3.90e-4 | |||
| Control vs restored, q = 0.16, p = 0.99 | |||
| FNΔ2 vs restored, q = 5.99, p = 8.38e-5 | |||
| 3B | Growth curve | Two-way ANOVA | Interaction F(18,294) = 19.75, p < 1.00e-15 |
| Females | Time: F(9,294) = 158.4, p < 1.00e-15 | ||
| Genotype: F(2,294) = 473.2, p < 1.00e-15 | |||
| Tukey’s multiple comparisons test | |||
| Four weeks: | |||
| Control vs FNΔ2, q = 1.98, p = 0.34 | |||
| Control vs restored, q = 1.13, p = 0.71 | |||
| FNΔ2 vs restored, q = 2.99, p = 8.94e-2 | |||
| Five weeks: | |||
| Control vs FNΔ2, q = 4.11, p = 1.10e-2 | |||
| Control vs restored, q = 1.88, p = 0.38 | |||
| FNΔ2 vs restored, q = 5.82, p = 1.48e-4 | |||
| Six weeks: | |||
| Control vs FNΔ2, q = 7.80, p = 2.32e-7 | |||
| Control vs restored, q = 1.69, p = 0.46 | |||
| FNΔ2 vs restored, q = 9.55, p = 2.31e-10 | |||
| 3C | Normal | One-way ANOVA | F(2,23) = 138.4, p < 15.1e-14 |
| Fat mass, males | distribution | Tukey’s multiple comparisons test | |
| Control vs FNΔ2, q = 19.97, p = 2.39e-12 | |||
| Control vs restored, q = 0.05, p > 0.99 | |||
| FNΔ2 vs restored, q = 21.10, p = 7.78e-13 | |||
| 3C | Normal | One-way ANOVA | F(2,23) = 0.167, p = 0.85 |
| Lean mass, males | distribution | Tukey’s multiple comparisons test | |
| Control vs FNΔ2, q = 0.50, p = 0.93 | |||
| Control vs restored, q = 0.29, p = 0.98 | |||
| FNΔ2 vs restored, q = 0.81, p = 0.84 | |||
| 3D | Normal | One-way ANOVA | F(2,18) = 138.4, p = 1.18e-11 |
| Fat mass, females | distribution | Tukey’s multiple comparisons test | |
| Control vs FNΔ2, q = 21.01, p = 4.51e-11 | |||
| Control vs restored, q = 0.33, p = 0.97 | |||
| FNΔ2 vs restored, q = 21.98, p = 2.09e-12 | |||
| 3D | Normal | One-way ANOVA | F(2,18) = 6.16, p = 9.17e-3 |
| Lean mass, females | distribution | Tukey’s multiple comparisons test | |
| Control vs FNΔ2, q = 3.24, p = 0.08 | |||
| Control vs restored, q = 1.83, p = 0.42 | |||
| FNΔ2 vs restored, q = 4.96, p = 6.74e-3 | |||
| 3E | Normal | One-way ANOVA | F(2,20) = 157.4, p = 5.80e-14 |
| Gonadal fat, males | distribution | Tukey’s multiple comparisons test | |
| Control vs FNΔ2, q = 22.76, p = 2.00e-12 | |||
| Control vs restored, q = 0.51, p = 0.93 | |||
| FNΔ2 vs restored, q = 23.51, p = 1.09e-12 | |||
| 3E | Normal | One-way ANOVA | F(2,19) = 354.5, p < 1.00e-15 |
| Inguinal fat, males | distribution | Tukey’s multiple comparisons test | |
| Control vs FNΔ2, q = 34.87, p < 1.00e-15 | |||
| Control vs restored, q = 0.60, p = 0.91 | |||
| FNΔ2 vs restored, q = 34.40, p < 1.00e-15 | |||
| 3F | Normal | One-way ANOVA | F(2,18) = 173.8, p = 1.70e-12 |
| Gonadal fat, females | distribution | Tukey’s multiple comparisons test | |
| Control vs FNΔ2, q = 24.08, p = 4.26e-12 | |||
| Control vs restored, q = 0.62, p = 0.90 | |||
| FNΔ2 vs restored, q = 25.06, p = 2.12e-12 | |||
| 3F | Normal | One-way ANOVA | F(2,17) = 57.55, p = 2.70e-8 |
| Inguinal fat, females | distribution | Tukey’s multiple comparisons test | |
| Control vs FNΔ2, q = 13.68, p = 7.26e-8 | |||
| Control vs restored, q = 0.20, p = 0.99 | |||
| FNΔ2 vs restored, q = 14.49, p = 3.12e-8 | |||
| 4F | Normal | Two-way ANOVA | Interaction F(1,36) = 3.207, p = 0.11 |
| distribution | Genotype: F(1,36) = 3.61e-5, p = 0.99 | ||
| Detection: F(1,36) = 45.97, p = 6.39e-8 | |||
| Tukey’s multiple comparisons test | |||
| Control-A568 vs restored-A568, q = 1.57, p = 0.69 | |||
| Control-A568 vs control-DAB, q = 5.24, p = 3.76e-3 | |||
| Control-A568 vs restored-DAB, q = 6.65, p = 2.10e-4 | |||
| Restored-A568 vs control-DAB, q = 6.92, p = 1.19e-4 | |||
| Restored-A568 vs restored-DAB, q = 8.26, p = 6.60e-6 | |||
| Control-DAB vs restored-DAB, q = 1.74, p = 0.61 | |||
| 4F | Normal distribution | One-way ANOVA | F(2,51) = 24.9, p = 2.85e-8Tukey’s multiple comparisons testA568 vs DAB, q = 9.97, p = 1.35e-8A548 vs A488, q = 4.58, p = 5.87e-3DAB vs A488, q = 4.74, p = 4.31e-3 |
| 5 (data not shown) | Normal | Student’s t test | t = 10.75, df = 13, p = 7.76e-8 |
| # of Pomc neurons | distribution | ||
| 5E | Normal | Two-way RM ANOVA | Interaction F(1,12) = 20.23, p = 7.30e-4 |
| distribution | Genotype: F(1,12) = 3.181, p = 9.98e-2 | ||
| Marker: F(1,12) = 1.363, p = 0.27 | |||
| Sidak’s multiple comparisons test | |||
| Control-Vglut2 + vs restored-Vglut2 +, t = 4.37, p = 4.10e-4 | |||
| Control-Gad67 + vs restored-Gad67 +, t = 1.76, p = 0.17 | |||
| Control-Vglut2 + vs control-Gad67 +, t = 3.75, p = 5.56e-3 | |||
| Restored-Vglut2 + vs restored-Gad67 +, t = 2.54, p = 5.09e-2 | |||
| 5E (data not shown) | Normal | Student’s t test | t = 4.498, df = 12, p = 7.30e-4 |
| Difference | distribution | ||
| 5F | Normal | Two-way RM ANOVA | Interaction F(1,12) = 23.86, p = 3.76e-4 |
| distribution | Genotype: F(1,12) = 46.4, p = 1.87e-5 | ||
| Marker: F(1,12) = 4.797, p = 4.90e-2 | |||
| Sidak’s multiple comparisons test | |||
| Control-Vglut2 + vs restored-Vglut2 +, t = 3.96, p = 1.17e-3 | |||
| Control-Gad67 + vs restored-Gad67 +, t = 8.27, p = 3.50e-8 | |||
| Control-Vglut2 + vs control-Gad67 +, t = 4.68, p = 1.07e-3 | |||
| Restored-Vglut2 + vs restored-Gad67 +, t = 2.06, p = 0.12 | |||
| 5E (data not shown) | Normal | Student’s t test | t = 4.884, df = 12, p = 3.76e-4 |
| Difference | distribution | ||
| 5G | Normal | One-way ANOVA | F(2,32) = 10.63, p = 2.88e-4 |
| distribution | Tukey’s multiple comparisons test | ||
| Control vs FNΔ2, q = 5.96, p = 5.43e-4 | |||
| Control vs restored, q = 0.65, p = 0.89 | |||
| FNΔ2 vs restored, q = 6.34, p = 2.54e-4 | |||
| 6M | Normal | Two-way RM ANOVA | Interaction F(12,60) = 13.10, p = 1.19e-12 |
| distribution | Neurotransmitter: F(3,15) = 47.14, p = 7.16e-8 | ||
| Level: F(4,20) = 3.16, p = 3.63e-2 | |||
| Tukey’s multiple comparisons test | |||
| Level 1 vs level 2, q = 3.71, p = 0.10 | |||
| Level 1 vs level 3, q = 1.42, p = 0.85 | |||
| Level 1 vs level 4, q = 2.70, p = 0.35 | |||
| Level 1 vs level 5, q = 0.52, p > 0.99 | |||
| Level 2 vs level 3, q = 2.29, p = 0.50 | |||
| Level 2 vs level 4, q = 1.01, p = 0.95 | |||
| Level 2 vs level 5, q = 4.23, p = 5.02e-2 | |||
| Level 3 vs level 4, q = 1.28, p = 0.89 | |||
| Level 3 vs level 5, q = 1.94, p = 0.65 | |||
| Level 4 vs level 5, q = 3.22, p = 0.19 | |||
| 6N | Normal | Two-way RM ANOVA | Interaction F(12,60) = 13.10, p = 1.19e-12 |
| distribution | Neurotransmitter: F(3,15) = 47.14, p = 7.16e-8 | ||
| Level: F(4,20) = 3.16, p = 3.63e-2 | |||
| Tukey’s multiple comparisons test | |||
| Vglut2 + vs Gad67 +, q = 6.87, p = 1.07e-3 | |||
| Vglut2 + vs Vglut2/Gad67 +, q = 8.29, p = 1.66e-4 | |||
| Vglut2 + vs Pomc-only, q = 6.62, p = 1.51e-3 | |||
| Gad67 + vs Vglut2/Gad67 +, q = 1.42, p = 0.75 | |||
| Gad67 + vs Pomc-only, q = 13.49, p = 5.09e-7 | |||
| Vglut2/Gad67 + vs Pomc-only, q = 14.90, p = 1.37e-7 | |||
| 6O | Normal | Two-way RM ANOVA | Interaction F(12,60) = 13.10, p = 1.19e-12 |
| distribution | Neurotransmitter: F(3,15) = 47.14, p = 7.16e-8 | ||
| Level: F(4,20) = 3.16, p = 3.63e-2 | |||
| Tukey’s multiple comparisons test | |||
| Vglut2 +: | |||
| Level 1 vs level 2, q = 0.23, p = 0.99 | |||
| Level 1 vs level 3, q = 4.54, p = 1.75e-2 | |||
| Level 1 vs level 4, q = 3.39, p = 0.13 | |||
| Level 1 vs level 5, q = 7.18, p = 3.80e-5 | |||
| Level 2 vs level 3, q = 4.31, p = 2.71e-2 | |||
| Level 2 vs level 4, q = 3.16, p = 0.18 | |||
| Level 2 vs level 5, q = 6.96, p = 6.80e-5 | |||
| Level 3 vs level 4, q = 1.15, p = 0.93 | |||
| Level 3 vs level 5, q = 2.64, p = 0.35 | |||
| Level 4 vs level 5, q = 3.79, p = 6.85e-2 | |||
| Gad67 +: | |||
| Level 1 vs level 2, q = 7.05, p = 5.33e-5 | |||
| Level 1 vs level 3, q = 4.90, p = 8.36e-3 | |||
| Level 1 vs level 4, q = 1.50, p = 0.83 | |||
| Level 1 vs level 5, q = 7.18, p = 0.41 | |||
| Level 2 vs level 3, q = 2.15, p = 0.55 | |||
| Level 2 vs level 4, q = 5.55, p = 2.03e-3 | |||
| Level 2 vs level 5, q = 9.53, p = 6.85e-8 | |||
| Level 3 vs level 4, q = 3.40, p = 0.13 | |||
| Level 3 vs level 5, q = 7.38, p = 2.26e-5 | |||
| Level 4 vs level 5, q = 3.98, p = 4.98e-2 | |||
| Pomc-only: | |||
| Level 1 vs level 2, q = 1.10, p = 0.94 | |||
| Level 1 vs level 3, q = 1.59, p = 0.79 | |||
| Level 1 vs level 4, q = 1.56, p = 0.80 | |||
| Level 1 vs level 5, q = 2.77, p = 0.30 | |||
| Level 2 vs level 3, q = 0.49, p = 0.99 | |||
| Level 2 vs level 4, q = 0.46, p = 0.99 | |||
| Level 2 vs level 5, q = 1.67, p = 0.76 | |||
| Level 3 vs level 4, q = 0.03, p = 0.99 | |||
| Level 3 vs level 5, q = 1.18, p = 0.92 | |||
| Level 4 vs level 5, q = 1.21, p = 0.91 | |||
| Vglut2/Gad67 +: | |||
| Level 1 vs level 2, q = 6.44, p = 2.51e-4 | |||
| Level 1 vs level 3, q = 5.88, p = 9.63e-4 | |||
| Level 1 vs level 4, q = 12.31, p = 5.13e-11 | |||
| Level 1 vs level 5, q = 10.71, p = 2.63e-9 | |||
| Level 2 vs level 3, q = 0.56, p = 0.99 | |||
| Level 2 vs level 4, q = 5.87, p = 9.77e-4 | |||
| Level 2 vs level 5, q = 4.27, p = 2.92e-2 | |||
| Level 3 vs level 4, q = 6.43, p = 5.54e-4 | |||
| Level 3 vs level 5, q = 4.83, p = 9.68e-3 | |||
| Level 4 vs level 5, q = 1.60, p = 0.79 | |||
| Level 1: | |||
| Vglut2 + vs Gad67 +, q = 1.14, p = 0.85 | |||
| Vglut2 + vs Vglut2/Gad67 +, q = 5.16, p = 3.00e-3 | |||
| Vglut2 + vs Pomc-only, q = 5.63, p = 1.05e-3 | |||
| Gad67 + vs Vglut2/Gad67 +, q = 4.02, p = 3.02e-2 | |||
| Gad67 + vs Pomc-only, q = 4.49, p = 1.23e-2 | |||
| Vglut2/Gad67 + vs Pomc-only, q = 0.47, p = 0.99 | |||
| Level 2: | |||
| Vglut2 + vs Gad67 +, q = 6.14, p = 3.18e-4 | |||
| Vglut2 + vs Vglut2/Gad67 +, q = 1.50, p = 0.72 | |||
| Vglut2 + vs Pomc-only, q = 6.51, p = 1.29e-4 | |||
| Gad67 + vs Vglut2/Gad67 +, q = 4.64, p = 9.16e-3 | |||
| Gad67 + vs Pomc-only, q = 12.64, p = 2.74e-11 | |||
| Vglut2/Gad67 + vs Pomc-only, q = 8.00, p = 2.67e-6 | |||
| Level 3: | |||
| Vglut2 + vs Gad67 +, q = 8.30, p = 1.20e-6 | |||
| Vglut2 + vs Vglut2/Gad67 +, q = 5.25, p = 2.48e-3 | |||
| Vglut2 + vs Pomc-only, q = 2.68, p = 0.24 | |||
| Gad67 + vs Vglut2/Gad67 +, q = 3.05, p = 0.15 | |||
| Gad67 + vs Pomc-only, q = 10.99, p = 7.50e-10 | |||
| Vglut2/Gad67 + vs Pomc-only, q = 7.94, p = 3.19e-6 | |||
| Level 4: | |||
| Vglut2 + vs Gad67 +, q = 3.75, p = 4.92e-2 | |||
| Vglut2 + vs Vglut2/Gad67 +, q = 10.53, p = 2.60e-9 | |||
| Vglut2 + vs Pomc-only, q = 3.80, p = 4.45e-2 | |||
| Gad67 + vs Vglut2/Gad67 +, q = 6.78, p = 6.41e-5 | |||
| Gad67 + vs Pomc-only, q = 7.55, p = 8.88e-6 | |||
| Vglut2/Gad67 + vs Pomc-only, q = 14.33, p = 2.00e-11 | |||
| Level 5: | |||
| Vglut2 + vs Gad67 +, q = 3.56, p = 6.73e-2 | |||
| Vglut2 + vs Vglut2/Gad67 +, q = 12.73, p = 2.58e-11 | |||
| Vglut2 + vs Pomc-only, q = 1.22, p = 0.83 | |||
| Gad67 + vs Vglut2/Gad67 +, q = 9.17, p = 1.13e-7 | |||
| Gad67 + vs Pomc-only, q = 4.78, p = 6.89e-3 | |||
| Vglut2/Gad67 + vs Pomc-only, q = 13.94, p = 2.01e-11 | |||
| 6P | Normal | Two-way RM ANOVA | Interaction F(12,60) = 11.47, p = 1.69e-11 |
| distribution | Neurotransmitter: F(3,15) = 2.105, p = 0.14 | ||
| Level: F(4,20) = 3.205, p = 3.46e-2 | |||
| Tukey’s multiple comparisons test | |||
| Vglut2 +: | |||
| Level 1 vs level 2, q = 0.45, p = 0.99 | |||
| Level 1 vs level 3, q = 5.48, p = 2.42e-3 | |||
| Level 1 vs level 4, q = 3.95, p = 5.22e-2 | |||
| Level 1 vs level 5, q = 8.61, p = 8.65e-7 | |||
| Level 2 vs level 3, q = 5.02, p = 6.49e-3 | |||
| Level 2 vs level 4, q = 3.50, p = 0.11 | |||
| Level 2 vs level 5, q = 8.16, p = 2.92e-6 | |||
| Level 3 vs level 4, q = 1.52, p = 0.82 | |||
| Level 3 vs level 5, q = 3.13, p = 0.19 | |||
| Level 4 vs level 5, q = 4.65, p = 1.39e-2 | |||
| Gad67 +: | |||
| Level 1 vs level 2, q = 5.36, p = 3.13e-3 | |||
| Level 1 vs level 3, q = 3.76, p = 7.27e-2 | |||
| Level 1 vs level 4, q = 1.37, p = 0.87 | |||
| Level 1 vs level 5, q = 1.54, p = 0.81 | |||
| Level 2 vs level 3, q = 1.60, p = 0.79 | |||
| Level 2 vs level 4, q = 4.00, p = 4.85e-2 | |||
| Level 2 vs level 5, q = 6.90, p = 7.79e-5 | |||
| Level 3 vs level 4, q = 2.39, p = 0.45 | |||
| Level 3 vs level 5, q = 5.30, p = 3.56e-3 | |||
| Level 4 vs level 5, q = 2.91, p = 0.25 | |||
| Pomc-only: | |||
| Level 1 vs level 2, q = 4.81, p = 1.02e-2 | |||
| Level 1 vs level 3, q = 6.05, p = 6.39e-4 | |||
| Level 1 vs level 4, q = 6.88, p = 8.36e-5 | |||
| Level 1 vs level 5, q = 11.14, p = 8.14e-9 | |||
| Level 2 vs level 3, q = 1.24, p = 0.90 | |||
| Level 2 vs level 4, q = 2.07, p = 0.59 | |||
| Level 2 vs level 5, q = 6.33, p = 3.27e-4 | |||
| Level 3 vs level 4, q = 0.83, p = 0.98 | |||
| Level 3 vs level 5, q = 5.09, p = 5.66e-3 | |||
| Level 4 vs level 5, q = 4.26, p = 2.98e-2 | |||
| Vglut2/Gad67 +: | |||
| Level 1 vs level 2, q = 4.02, p = 4.68e-2 | |||
| Level 1 vs level 3, q = 3.69, p = 8.14e-2 | |||
| Level 1 vs level 4, q = 7.75, p = 8.64e-6 | |||
| Level 1 vs level 5, q = 7.01, p = 6.00e-5 | |||
| Level 2 vs level 3, q = 0.32, p = 0.99 | |||
| Level 2 vs level 4, q = 3.74, p = 7.55e-2 | |||
| Level 2 vs level 5, q = 2.99, p = 0.23 | |||
| Level 3 vs level 4, q = 4.06, p = 4.31e-2 | |||
| Level 3 vs level 5, q = 3.32, p = 0.15 | |||
| Level 4 vs level 5, q = 0.75, p = 0.98 | |||
| Level 1: | |||
| Vglut2 + vs Gad67 +, q = 5.49, p = 1.47e-3 | |||
| Vglut2 + vs Vglut2/Gad67 +, q = 8.19, p = 1.62e-6 | |||
| Vglut2 + vs Pomc-only, q = 2.08, p = 0.46 | |||
| Gad67 + vs Vglut2/Gad67 +, q = 2.70, p = 0.23 | |||
| Gad67 + vs Pomc-only, q = 7.56, p = 8.58e-6 | |||
| Vglut2/Gad67 + vs Pomc-only, q = 10.27, p = 5.40e-8 | |||
| Level 2: | |||
| Vglut2 + vs Gad67 +, q = 0.33, p = 0.99 | |||
| Vglut2 + vs Vglut2/Gad67 +, q = 3.72, p = 5.11e-2 | |||
| Vglut2 + vs Pomc-only, q = 2.28, p = 0.38 | |||
| Gad67 + vs Vglut2/Gad67 +, q = 4.05, p = 2.87e-2 | |||
| Gad67 + vs Pomc-only, q = 2.61, p = 0.26 | |||
| Vglut2/Gad67 + vs Pomc-only, q = 1.44, p = 0.74 | |||
| Level 3: | |||
| Vglut2 + vs Gad67 +, q = 3.75, p = 4.90e-2 | |||
| Vglut2 + vs Vglut2/Gad67 +, q = 0.98, p = 0.90 | |||
| Vglut2 + vs Pomc-only, q = 1.50, p = 0.71 | |||
| Gad67 + vs Vglut2/Gad67 +, q = 2.77, p = 0.21 | |||
| Gad67 + vs Pomc-only, q = 2.25, p = 0.39 | |||
| Vglut2/Gad67 + vs Pomc-only, q = 0.53, p = 0.98 | |||
| Level 4: | |||
| Vglut2 + vs Gad67 +, q = 0.17, p = 0.99 | |||
| Vglut2 + vs Vglut2/Gad67 +, q = 3.51, p = 7.26e-2 | |||
| Vglut2 + vs Pomc-only, q = 0.85, p = 0.98 | |||
| Gad67 + vs Vglut2/Gad67 +, q = 3.68, p = 5.50e-2 | |||
| Gad67 + vs Pomc-only, q = 0.68, p = 0.96 | |||
| Vglut2/Gad67 + vs Pomc-only, q = 4.36, p = 1.60e-2 | |||
| Level 5: | |||
| Vglut2 + vs Gad67 +, q = 1.58, p = 0.68 | |||
| Vglut2 + vs Vglut2/Gad67 +, q = 7.42, p = 1.24e-5 | |||
| Vglut2 + vs Pomc-only, q = 0.45, p = 0.99 | |||
| Gad67 + vs Vglut2/Gad67 +, q = 5.85, p = 6.39e-4 | |||
| Gad67 + vs Pomc-only, q = 2.03, p = 0.48 | |||
| Vglut2/Gad67 + vs Pomc-only, q = 7.88, p = 3.74e-6 | |||
| 6P | Normal | Linear regression | Slopes: F(3,11) = 20.84, p = 7.66e-5 |
| distribution | Vglut2 +: | ||
| F(1,28) = 33.87, p = 2.97e-6, R 2 = 0.83 | |||
| Gad67 + (levels 2–5): | |||
| F(1,22) = 57.49, p = 1.42e-7, R 2 = 0.98 | |||
| Pomc-only: | |||
| F(1,28) = 23.72, p = 3.95e-5, R 2 = 0.92 | |||
| Vglut2/Gad67 +: | |||
| F(1,28) = 39.83, p = 7.95e-7, R 2 = 0.83 | |||