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. 2018 Oct 12;111(4):350–364. doi: 10.1093/jnci/djy132

Table 1.

Baseline characteristics of participants in the CIMBA consortium with genotype information*

Variable BRCA1 carriers BRCA2 carriers
N = 14 676 N = 7912
Case participants, n 7360 4091
 Year of birth, median (IQR) 1956 (1948–1964) 1954 (1945–1961)
 Age at diagnosis, mean (SD), y 41.1 (9.3) 44.2 (10.0)
Control participants, n 7316 3821
 Year of birth, median (IQR) 1963 (1953–1972) 1962 (1950–1971)
 Age at censoring, mean (SD), y 42.0 (12.5) 44.0 (13.5)
Ethnicity, n (%)
 Caucasian, not otherwise specified 13 435 (91.5) 7126 (90.1)
 Ashkenazi Jewish 1241 (8.5) 786 (9.9)
Height in cm, n 4502 3155
 Mean (SD) 164.8 (6.8) 164.5 (6.9)
Weight at date of questionnaire in kg, n 4436 3133
 Mean (SD) 68.1 (13.9) 69.0 (14.5)
BMI at date of questionnaire in kg/m2, n 4401 3115
 Mean (SD) 25.1 (5.1) 25.6 (5.2)
Weight in early adulthood in kg, n 3152 2296
 Mean (SD) 57.6 (9.2) 57.9 (9.6)
BMI in early adulthood in kg/m2, n 3134 2283
 Mean (SD) 21.2 (3.3) 21.4 (3.3)
Age at menarche in years, n 4425 3034
 Mean (SD), y 13.0 (1.5) 13.0 (1.5)
Parous, n (%)
 Yes 3914 (77.8) 2681(79.7)
 No 1117 (22.2) 682 (20.3)
Age at first live birth in years, n 3711 2579
 Mean (SD), y 25.3 (4.9) 25.3 (4.9)
Menopausal status, n (%)
 Premenopausal 2330 (47.4) 1610 (46.4)
 Postmenopausal 2588 (52.6) 1858 (53.6)
Age at menopause, mean (SD), y 44.7 (6.0) 45.6 (6.0)

*BMI = body mass index; CIMBA = Consortium of Investigators of Modifiers of BRCA1/2; IQR = interquartile range.