FIGURE 5.

Experimental results corresponding to the cassette studied by the simulations shown in Fig. 3. (A) Per-site mutation frequencies. (B) Decay of entropy density as a function of word length, for words centered at the center of the (hot hot’) cluster on the far left (blue), the middle (orange) and the far right (green). Consistent with the simulations, the words are shortest on the far left, suggesting that AID diffusion is slowest here, while the words are longest in the middle of the cassette, indicating that AID diffusion is fastest there.