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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Clin Nucl Med. 2019 May;44(5):377–385. doi: 10.1097/RLU.0000000000002533

Figure 4. Parametric values of [18F]NaF uptake for different bone tissue types of the knee.

Figure 4

Cortical bone had the highest [18F]NaF uptake in all measured parameters when compared to trabecular bone, which had the lowest uptake. Subchondral bone also had higher uptake than trabecular bone with significantly higher SUVmean, SUVmax and KiNLR values, yet only slightly elevated K1 and k3/(k3+k2) values. The relative distribution of KiNLR values between bone tissues was almost identical to that of SUV. Note that despite having the highest uptake as expressed by SUV and KiNLR, cortical bone has the lowest extraction fraction. P values were corrected for 18 comparisons using a Bonferroni correction. († p<0.01 difference compared to cortical bone, ‡ p<0.01 difference between trabecular bone and subchondral bone)