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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2019 Feb 7;28(4):731–740. doi: 10.1158/1055-9965.EPI-18-0966

Figure 2. β-diversity in normal lung tissue and survival.

Figure 2.

Principal coordinate analysis of the Bray-Curtis dissimilarity, with samples annotated according to recurrence status, histology, and person days: (a) non-rarefied, (b) rarefied to an even depth of 63 sequence reads per sample. (c) Unsupervised clustering (ward.D2 method) of the Bray-Curtis dissimilarity grouped patients into four clusters. These clusters were significantly related to (d) recurrence-free survival (log-rank p = 0.031) and (e) disease-free survival (log-rank p = 0.015).